KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYROXD1
All Species:
36.36
Human Site:
T470
Identified Species:
66.67
UniProt:
Q8WU10
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU10
NP_079130.2
500
55793
T470
G
E
T
D
L
E
E
T
F
E
N
L
I
L
N
Chimpanzee
Pan troglodytes
XP_520786
500
55723
T470
G
E
T
D
L
E
E
T
F
E
N
L
I
L
N
Rhesus Macaque
Macaca mulatta
XP_001098386
500
55757
T470
G
E
T
D
L
E
E
T
F
E
N
L
I
L
N
Dog
Lupus familis
XP_534871
564
62639
T535
G
E
T
D
L
E
E
T
F
E
H
L
I
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3TMV7
498
55573
T468
G
E
T
D
L
E
E
T
F
E
N
L
I
L
N
Rat
Rattus norvegicus
Q68FS6
498
55471
T468
G
E
T
D
L
E
E
T
F
E
N
L
I
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507787
271
29578
D242
E
K
I
R
D
E
T
D
A
V
G
S
A
L
G
Chicken
Gallus gallus
XP_416422
500
55202
T470
G
E
T
D
L
E
E
T
F
E
N
L
I
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PBT5
490
54238
T460
G
E
T
D
L
E
E
T
F
E
N
L
I
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610023
472
52333
C443
N
T
D
L
A
E
T
C
E
N
L
I
L
N
G
Honey Bee
Apis mellifera
XP_624926
477
53873
C448
D
T
N
L
E
E
M
C
E
N
L
I
L
N
Q
Nematode Worm
Caenorhab. elegans
NP_495754
451
50706
L422
E
T
D
M
E
E
T
L
E
N
L
I
L
N
K
Sea Urchin
Strong. purpuratus
XP_782117
495
54197
T465
G
D
T
D
L
E
E
T
F
E
N
L
I
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.1
74.6
N.A.
85
85.1
N.A.
40.2
77
N.A.
64
N.A.
46.4
50
32.7
57.4
Protein Similarity:
100
99.5
98
81.2
N.A.
90.8
91.5
N.A.
44.4
86.8
N.A.
80.4
N.A.
62.2
66
54
72.2
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
13.3
100
N.A.
100
N.A.
6.6
6.6
6.6
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
N.A.
100
N.A.
20
20
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% C
% Asp:
8
8
16
70
8
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
16
62
0
0
16
100
70
0
24
70
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% F
% Gly:
70
0
0
0
0
0
0
0
0
0
8
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
24
70
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
16
70
0
0
8
0
0
24
70
24
77
0
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
24
62
0
0
24
70
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% S
% Thr:
0
24
70
0
0
0
24
70
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _